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结节性多动脉炎患者因肾周包膜下血肿继发高肾素性高血压。

Hyperreninemic hypertension secondary to a subcapsular perinephric hematoma in a patient with polyarteritis nodosa.

作者信息

Pintar T J, Zimmerman S

机构信息

University of Wisconsin Madison Hospital and Clinics 53792, USA.

出版信息

Am J Kidney Dis. 1998 Sep;32(3):503-7. doi: 10.1053/ajkd.1998.v32.pm9740170.

Abstract

Page kidney is the name ascribed to a rare syndrome of hyperreninemic hypertension caused by unilateral compressive perinephritis. Blood or fluid that accumulates in the perinephric subcapsular space compresses the renal parenchyma leading to ischemia. This syndrome is analogous to the description of cellophane-induced perinephritis by Page in 1939. Page kidney typically presents in healthy young men after blunt trauma to the flank or abdomen, although cases have been noted after medical or surgical interventions. We report a case of a Page kidney in a young man with hepatitis B virus-associated polyarteritis nodosa. The patient presented with severe hypertension, hypokalemia, hyperreninemia, and radiographic evidence of a unilateral subcapsular hematoma. Perinephric hemorrhage developed because of necrotizing vascular inflammation and spontaneous or traumatic vascular rupture. In patients who present with new-onset hypertension and hypokalemia with a history of trauma or coexisting vasculitis, the presence of a Page kidney should be considered.

摘要

佩奇肾是一种因单侧压迫性肾周炎引起的高肾素血症性高血压罕见综合征的名称。积聚在肾周包膜下间隙的血液或液体压迫肾实质,导致缺血。该综合征类似于1939年佩奇对玻璃纸诱导性肾周炎的描述。佩奇肾通常在健康年轻男性遭受侧腹或腹部钝性创伤后出现,不过在医疗或外科手术后也有病例报道。我们报告一例患有乙型肝炎病毒相关性结节性多动脉炎的年轻男性佩奇肾病例。该患者表现为严重高血压、低钾血症、高肾素血症以及单侧包膜下血肿的影像学证据。肾周出血是由坏死性血管炎症和自发性或外伤性血管破裂引起的。对于出现新发高血压和低钾血症且有创伤史或并存血管炎的患者,应考虑佩奇肾的存在。

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