Nzerue Chike M, Carew Kehinde, Faulkner Marquetta, Torrente Sandra, Fleming Mary
Department of Medicine, Nashville General Hospital, 1818 Albion Street, Nashville, TN, USA.
Department of Obstetrics and Gynecology, Nashville General Hospital, 1818 Albion Street, Nashville, TN, USA.
NDT Plus. 2010 Jun;3(3):265-268. doi: 10.1093/ndtplus/sfq015. Epub 2010 Feb 28.
Cocaine abuse may contribute to the diverse forms of renal injury. We report a case of a pregnant woman who developed a large subcapsular renal haematoma after cocaine intoxication at 18-week gestation. She stabilized on conservative management and presented again at 29-week gestation with pre-eclampsia, acute renal failure and fetal demise. She required caesarean section delivery and intensive antihypertensive therapy to control severe pre-eclampsia associated with cocaine intoxication. This case is unique in that it is the first report of cocaine intoxication in pregnancy complicated by subcapsular haemorrhage. We discuss the possible mechanisms for the occurrence of this complication.
可卡因滥用可能导致多种形式的肾损伤。我们报告一例孕妇，在妊娠18周时因可卡因中毒后出现巨大肾包膜下血肿。她经保守治疗病情稳定，在妊娠29周时再次出现子痫前期、急性肾衰竭和胎儿死亡。她需要剖宫产分娩并进行强化抗高血压治疗以控制与可卡因中毒相关的严重子痫前期。该病例的独特之处在于它是妊娠期间可卡因中毒并发包膜下出血的首例报告。我们讨论了这种并发症发生的可能机制。
