Lindheim S R, Frumovitz M, Sauer M V
Department of Obstetrics and Gynecology, Columbia University College of Physicians & Surgeons, The Center for Human Reproduction, New York, NY, USA.
Hum Reprod. 1998 Jul;13(7):2020-4. doi: 10.1093/humrep/13.7.2020.
We have reviewed the demographic characteristics of, and report abnormalities noted in, the de-novo growth and development of a paid oocyte donation programme. The personal profiles of all prospective oocyte donors were reviewed. Acceptance or rejection of candidates was based upon screening the results of medical, genetic and psychological testing. A total of 603 candidates initially responded to our advertisement. From this pool, 313 individuals were considered suitable and contacted by telephone. Following further conversation, 176 women were scheduled an entry interview. On completion of the formal screening process, 17.6% (n = 31) of those actually interviewed were denied entry. Thus, from the initial interested parties, only 23% of women wishing to participate in oocyte donation were considered suitable candidates. Given the high attrition rate, we concluded that the need for rigorous and thorough medical, psychological and genetic testing is mandatory for the establishment of a donor registry. Furthermore, professional counselling of prospective donors with respect to the results of tests and the implications of test results with respect to their future medical and reproductive health, are important parts of providing comprehensive care.
我们回顾了一项有偿卵母细胞捐赠计划从头开始的增长和发展的人口统计学特征，并报告了其中发现的异常情况。我们审查了所有潜在卵母细胞捐赠者的个人资料。候选人的接受或拒绝是基于医学、基因和心理测试的筛查结果。共有603名候选人最初回应了我们的广告。在这些人中，313人被认为合适并通过电话联系。经过进一步交谈，176名女性被安排进行入职面试。在正式筛查过程完成后，实际接受面试的人中有17.6%（n = 31）被拒绝进入。因此，在最初感兴趣的人群中，只有23%希望参与卵母细胞捐赠的女性被认为是合适的候选人。鉴于高损耗率，我们得出结论，建立捐赠者登记册必须进行严格彻底的医学、心理和基因测试。此外，就测试结果及其对未来医疗和生殖健康的影响为准捐赠者提供专业咨询，是提供全面护理的重要组成部分。
