Viktrup L, Hée P
Department of Obstetrics and Gynecology, Glostrup County Hospital, University of Copenhagen, Denmark.
Acta Obstet Gynecol Scand. 1998 Aug;77(7):746-50.
The purpose of this study was to determine the long-term outcome after an appendectomy during pregnancy, especially focusing on fertility.
The Danish National Registry of Patients identified 117 pregnant women who had had an appendectomy during the period 1980 to 1985. One hundred-and-one of these women answered a questionnaire designed to focus on long-term complications, including infertility, during a 4 to 9 year period after the appendectomy. More than a 2-year attempt to conceive was defined as infertility.
Of the 101 women 15 with a normal appendix had a new intraperitoneal operation due to different indications. Three of these women had intraperitoneal adhesions. In one patient, adhesions were located on the Fallopian Tube but the location did not influence fertility. Five of the 101 women complained of infertility as defined; all had a normal appendix and none had intraperitoneal surgery during the observation period. Two of these five women conceived later during the observation period; one had confounding female and male infertility factors and two were not examined.
Appendectomy during pregnancy of a normal, inflamed or perforated appendix does not seem to cause clinically significant intraperitoneal adhesions or infertility later in life.
本研究的目的是确定孕期行阑尾切除术后的长期结局，尤其关注生育能力。
丹麦国家患者登记处识别出1980年至1985年期间行阑尾切除术的117名孕妇。其中101名女性回答了一份旨在关注阑尾切除术后4至9年期间包括不孕在内的长期并发症的问卷。超过2年的受孕尝试失败被定义为不孕。
101名女性中，15名阑尾正常的女性因不同指征进行了新的腹腔内手术。其中3名女性有腹腔粘连。1例患者粘连位于输卵管，但该位置不影响生育能力。101名女性中有5名主诉符合定义的不孕；她们阑尾均正常，且在观察期内均未进行腹腔内手术。这5名女性中有2名在观察期后期受孕；1名有复杂的男女不孕因素，2名未接受检查。
孕期对正常、发炎或穿孔的阑尾进行阑尾切除术似乎不会导致临床上显著的腹腔粘连或日后不孕。
