Zigmond S H
Biology Department, University of Pennsylvania, Philadelphia 19104-6018, USA.
Curr Biol. 1998 Sep 10;8(18):R654-7. doi: 10.1016/s0960-9822(07)00415-0.
Actin filament polymerization results primarily from the addition of monomers to pre-existing filaments. Recent studies have revealed that the Arp2/3 protein complex, which includes two actin-related proteins, can nucleate new actin filaments, and this capacity can be enhanced by ActA, a protein used by Listeria to polymerize actin.
肌动蛋白丝的聚合主要源于单体添加到已有的丝上。最近的研究表明,包含两种肌动蛋白相关蛋白的Arp2/3蛋白复合体能够使新的肌动蛋白丝成核,并且这种能力可以被ActA增强,ActA是一种被李斯特菌用来聚合肌动蛋白的蛋白。