Wandera A, Garcia G
University of Michigan, Department of Orthodontics and Pediatric Dentistry, Ann Arbor 48109-1078, USA.
ASDC J Dent Child. 1998 Jul-Aug;65(4):239-43, 229.
The purpose of this study was to compare in vitro effects of resin-modified and autopolymerizing glass ionomer restorative materials on demineralization of primary and permanent human enamel. Thirty primary and permanent enamel specimens measuring approximately 3 x 4 x 4 mm were sectioned and plano-paralleled before random placement of materials: Photac-Fil, a resin-modified glass ionomer; Ketac-Fil, an autopolymerizing glass ionomer; and Tytin, a silver amalgam. After incubation for twenty-four hours, the samples were pH cycled for eight hours at pH 5.0 and sixteen hours at pH 7.2 for a total of two weeks, all at 37 degrees C. The specimens were then subjected to an artificial caries challenge at pH 5.0 for 196 hours. The specimens were embeded in Epon 812 and incubated at 55 degrees C for thirty-six hours. Microsections were produced from each sample and subjected to microradiography and quantitative microdensitometry. Data on lesion depth and mineral content were analyzed by Two Way ANOVA and Student Newman-Keuls Pairwise Multiple Comparison tests. There were significant differences in lesion depth and mineral content between groups (p < 0.05) and between permanent and primary enamel. This study demonstrates that Photac-Fil and Ketac-Fil prevent in vitro demineralization at varying levels in primary and permanent enamel.
本研究的目的是比较树脂改性和自凝型玻璃离子修复材料对人乳牙和恒牙釉质脱矿的体外影响。将30个尺寸约为3×4×4mm的乳牙和恒牙釉质标本进行切片并磨平,然后随机放置材料:Photac-Fil,一种树脂改性玻璃离子;Ketac-Fil,一种自凝型玻璃离子;以及Tytin,一种银汞合金。孵育24小时后,样品在pH 5.0下进行8小时的pH循环,在pH 7.2下进行16小时的pH循环,共两周,均在37℃下进行。然后将标本在pH 5.0下进行196小时的人工龋损挑战。将标本嵌入Epon 812中,在55℃下孵育36小时。从每个样品制作显微切片,并进行显微放射照相和定量显微密度测定。通过双向方差分析和Student Newman-Keuls成对多重比较检验分析病变深度和矿物质含量的数据。各组之间以及恒牙和乳牙釉质之间在病变深度和矿物质含量上存在显著差异(p<0.05)。本研究表明,Photac-Fil和Ketac-Fil在不同程度上可预防乳牙和恒牙釉质的体外脱矿。