Rafel M, Esteve J, Cervantes F, Velasco M, Serra A, Campo E, Montserrat E
Servicio de Hematología, Hospital Clínic de Barcelona, Universidad de Barcelona.
Sangre (Barc). 1998 Jun;43(3):244-7.
A 47 year old woman with a MALT lymphoma affecting the breast exclusively is reported. Complete response was achieved after CHOP chemotherapy but three years later a relapse was observed. Second-line chemotherapy (CNOP) and local radiotherapy were administered, and a second remission was obtained lasting for 1 year at last follow-up. A bibliographic search of MALT lymphomas of the breast showed that most such cases correspond to localized forms (stage I-II) and that from the radiologic point of view nodular lesions are almost the rule, although in the present case diffuse involvement was observed. MALT lymphomas of the breast tend to remain localized, and to relapse locally, and these facts appear as independent of the treatment applied (surgery, radiotherapy, chemotherapy or any combination).
报道了一名47岁仅患有乳腺黏膜相关淋巴组织（MALT）淋巴瘤的女性。CHOP化疗后实现了完全缓解，但三年后出现复发。给予二线化疗（CNOP）和局部放疗，在最后一次随访时获得了持续1年的第二次缓解。对乳腺MALT淋巴瘤的文献检索显示，大多数此类病例为局限性形式（I-II期），从放射学角度来看，结节性病变几乎是常态，尽管在本病例中观察到弥漫性受累。乳腺MALT淋巴瘤倾向于保持局限性，并局部复发，而且这些情况似乎与所应用的治疗方法（手术、放疗、化疗或任何联合治疗）无关。
