Bernich E, Rubenstein R, Bellin J S
Biochim Biophys Acta. 1976 Nov 2;448(4):551-61. doi: 10.1016/0005-2736(76)90109-7.
The thermodynamic parameters which define transport of nonelectrolytes through bovine articular cartilage membranes were evaluated. H3HO, glucose and sucrose were used as permeants. These solutes permeate more readily through the upper layers (near the articular surface) than through the denser deeper layers approaching bone. Cartilage is similar in many respects to a swollen cellulose gel. Viscous-flow contributes importantly to transport within cartilage thus greatly enhancing the movement of nutrients.
评估了定义非电解质通过牛关节软骨膜转运的热力学参数。使用H3HO、葡萄糖和蔗糖作为渗透剂。这些溶质通过上层(靠近关节表面)比通过靠近骨骼的较致密深层更容易渗透。软骨在许多方面类似于肿胀的纤维素凝胶。粘性流动对软骨内的转运起重要作用,从而极大地促进了营养物质的移动。