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克罗地亚赫瓦尔岛人群中的VNTR DNA变异

VNTR DNA variation in the population of the island of Hvar, Croatia.

作者信息

Martinović I, Mastana S, Janićijević B, Jovanović V, Paphia S S, Roberts D F, Rudan P

机构信息

Institute for Anthropological Research, Zagreb, Croatia.

出版信息

Ann Hum Biol. 1998 Sep-Oct;25(5):489-99. doi: 10.1080/03014469800006722.

Abstract

The aim of this study was to investigate hypervariable DNA polymorphisms in the Croatian population. Two VNTR loci, D7S22 and D12S11, were studied in a sample of 68 inhabitants of the western and eastern regions of the island of Hvar. Binned allele frequencies and heterozygosity were calculated for the two regions and measures of genetic kinship and genetic distance were computed between the two regions and between each of these regions and nine world populations. The relatively large genetic distance between the two regions of the island of Hvar (0.0353) may reflect historical immigrations from the mainland and interesting peculiarities of the populations that arrived from the Balkan peninsula.

摘要

本研究的目的是调查克罗地亚人群中的高变DNA多态性。在赫瓦尔岛西部和东部地区的68名居民样本中研究了两个VNTR位点,即D7S22和D12S11。计算了这两个地区的等位基因频率和杂合度,并计算了这两个地区之间以及每个地区与九个世界人群之间的遗传亲缘关系和遗传距离指标。赫瓦尔岛两个地区之间相对较大的遗传距离(0.0353)可能反映了来自大陆的历史移民以及来自巴尔干半岛人群的有趣特性。

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