Kitajima K, Ikeda A, Terada K, Shibasaki H, Kimura J
Department of Neurology, Kyoto University Faculty of Medicine, Japan.
Rinsho Shinkeigaku. 1998 Apr;38(4):305-10.
A 25-year-old man manifesting gelastic seizure in association with hypothalamic hamartoma was reported. The epileptogenic focus was evaluated by long-term video EEG monitoring, single photon emission computed tomography (SPECT) and positron emission tomography (PET). Multiple independent ictal foci were found in the ictal EEG recording, and glucose metabolism and cerebral blood flow were decreased in scattered cortical areas. Facial asymmetry seen during gelastic seizure in this case may be caused by contraction of mimetic contralateral to the ictal focus in the temporal lobe.
报告了一名25岁患有与下丘脑错构瘤相关的痴笑发作的男性。通过长期视频脑电图监测、单光子发射计算机断层扫描（SPECT）和正电子发射断层扫描（PET）对致痫灶进行了评估。在发作期脑电图记录中发现了多个独立的发作期病灶，且在散在的皮质区域葡萄糖代谢和脑血流量降低。该病例中痴笑发作时出现的面部不对称可能是由颞叶发作灶对侧的模仿肌收缩所致。
