Kalita J, Misra U K
Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Electroencephalogr Clin Neurophysiol. 1998 Jul;107(1):39-43. doi: 10.1016/s0013-4694(98)00016-9.
The present study is aimed at describing electroencephalographic (EEG) changes in the tubercular meningitis (TBM) and correlating these with clinical and radiological findings.
All the patients underwent a detailed neurological evaluation, CSF analysis, EEG and CT scan studies. Outcome was assessed by the Barthel index (BI) score at the end of 3 months, into good (BI > or = 12) and poor (BI < 12). Thirty-two patients with TBM have been included of which 3 were definite and the remaining highly probable. Their mean age was 28 (range 8-62) years and 8 of whom were females. The majority of these patients were in stage III.
Clinical signs of raised intracranial tension were present in 9 and history of seizure in 11 patients. Cranial CT scan was abnormal in 22 patients. The CT scan abnormalities included hydrocephalus in 20, infarction in 11, exudates in 7 and tuberculoma in 4 patients. The EEG was abnormal in 24 patients. The EEG abnormalities included diffuse theta to delta slowing in 22 patients, intermittent rhythmic delta activity in frontal region in 15, right to left asymmetry in 5 and epileptiform discharges in 4 patients. At the end of 3 months, 5 patients died, 13 had poor, 3 partial and 11 complete recovery. The EEG findings correlated with the severity of meningitis, the degree of coma and outcome at 3 months as assessed by Barthel index score.
本研究旨在描述结核性脑膜炎（TBM）患者的脑电图（EEG）变化，并将这些变化与临床和影像学检查结果相关联。
所有患者均接受了详细的神经学评估、脑脊液分析、脑电图和CT扫描检查。在3个月末通过巴氏指数（BI）评分评估预后情况，分为良好（BI≥12）和不良（BI＜12）。纳入了32例结核性脑膜炎患者，其中3例确诊，其余高度疑似。他们的平均年龄为28岁（范围8 - 62岁），其中8例为女性。这些患者大多数处于Ⅲ期。
9例患者出现颅内压升高的临床体征，11例有癫痫发作史。22例患者的头颅CT扫描异常。CT扫描异常包括20例脑积水、11例梗死、7例渗出和4例结核瘤。24例患者脑电图异常。脑电图异常包括22例弥漫性θ波至δ波减慢、15例额叶间歇性节律性δ波活动、5例右向左不对称和4例癫痫样放电。3个月末，5例患者死亡，13例预后不良，3例部分恢复，11例完全恢复。脑电图结果与脑膜炎的严重程度、昏迷程度以及通过巴氏指数评分评估的3个月末的预后相关。
