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匹兹堡年轻人正常睡眠研究:聚焦清醒与睡眠脑电图频谱模式之间的关系。

The Pittsburgh study of normal sleep in young adults: focus on the relationship between waking and sleeping EEG spectral patterns.

作者信息

Ehlers C L, Kupfer D J, Buysse D J, Cluss P A, Miewald J M, Bisson E F, Grochocinski V J

机构信息

Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA, USA.

出版信息

Electroencephalogr Clin Neurophysiol. 1998 Mar;106(3):199-205. doi: 10.1016/s0013-4694(97)00130-2.

DOI:10.1016/s0013-4694(97)00130-2
PMID:9743277
Abstract

The effects of age and gender on spectral characteristics of the waking EEG were investigated in a large sample of young adult men and women. In addition, relationships between spectral characteristics of the waking and sleeping EEG within an individual were explored. The sample included 28 females and 33 males in two age groups: 20-29 years (n = 32), and 30-40 years (n = 29). Spectral analysis was used to quantify EEG frequency characteristics for waking EEG just prior to sleep onset, as well as for the entire sleep recording. Significant effects of age were seen in the waking EEG but only in the delta frequency range (0.5-4.5 Hz) with lower delta activity in the older group (F = 11.6, P = 0.001). No significant gender effects were found in the waking EEG. Independent of age and gender, spectral profiles in the delta, theta, alpha and beta frequency bands of a subject's waking EEG were found to be highly correlated with their sleep EEG. In addition, subjects with high voltage alpha profiles during waking were found to sleep significantly longer and deeper than those with low voltage records. Significant correlations between waking and sleep EEG suggest that the spectral signature of an individual's EEG may be found across sleep/wake states.

摘要

在大量年轻成年男性和女性样本中,研究了年龄和性别对清醒脑电图频谱特征的影响。此外,还探讨了个体清醒和睡眠脑电图频谱特征之间的关系。样本包括两个年龄组的28名女性和33名男性:20 - 29岁(n = 32)和30 - 40岁(n = 29)。频谱分析用于量化睡眠开始前清醒脑电图以及整个睡眠记录的脑电图频率特征。在清醒脑电图中观察到年龄的显著影响,但仅在δ频率范围(0.5 - 4.5 Hz),老年组的δ活动较低(F = 11.6,P = 0.001)。在清醒脑电图中未发现显著的性别影响。独立于年龄和性别,发现受试者清醒脑电图的δ、θ、α和β频段的频谱特征与他们的睡眠脑电图高度相关。此外,发现清醒时具有高电压α特征的受试者比低电压记录的受试者睡眠明显更长、更深。清醒和睡眠脑电图之间的显著相关性表明,个体脑电图的频谱特征可能在睡眠/清醒状态中都能找到。

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