Frank Ellen, Shear M Katherine, Rucci Paola, Banti Susanna, Mauri Mauro, Maser Jack D, Kupfer David J, Miniati Mario, Fagiolini Andrea, Cassano Giovanni B
Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.
Soc Psychiatry Psychiatr Epidemiol. 2005 Apr;40(4):283-90. doi: 10.1007/s00127-005-0893-2.
We sought to develop a series of assessment measures of psychiatric spectrum conditions associated with major DSM-IV mood and anxiety disorders that might capture the true phenotypes underlying these disorders. The specific objective of this report was to describe the methods we employed to create instruments that could cross linguistic and national boundaries and to evaluate the comparability of results obtained when one of these instruments, the Structured Clinical Interview for Panic-Agoraphobic Spectrum (SCI-PAS), was administered in the United States and in Italy.
After developing, in parallel, the English and the Italian versions of the SCI-PAS, identical protocols were conducted in patients and control samples at the University of Pittsburgh and the University of Pisa to examine the reliability and validity of the interview.
Total and domain scores on the SCI-PAS were strikingly similar in the US and Italian patient groups and in controls. In addition, similarly high levels of inter-rater and test-retest reliability were found at the two sites. Finally, virtually identical patterns of relationships were found between the domains of the SCI-PAS and established measures of the same constructs.
The SCI-PAS displays similar reliability and validity properties in the two versions. This suggests that the instrument taps a phenotype that is consistent in American and Italian patient and control populations.
我们试图开发一系列与《精神疾病诊断与统计手册》第四版（DSM-IV）中的主要心境和焦虑障碍相关的精神谱系状况评估措施，这些措施可能捕捉到这些障碍潜在的真实表型。本报告的具体目标是描述我们用于创建能够跨越语言和国家界限的工具的方法，并评估当其中一种工具——惊恐-广场恐怖谱系结构化临床访谈（SCI-PAS）在美国和意大利实施时所获得结果的可比性。
在并行开发SCI-PAS的英文和意大利文版本后，在匹兹堡大学和比萨大学的患者及对照样本中采用相同的方案来检验该访谈的信度和效度。
美国和意大利患者组以及对照组在SCI-PAS上的总分和各领域得分惊人地相似。此外，在两个地点发现了同样高水平的评分者间信度和重测信度。最后，在SCI-PAS的各领域与相同结构的既定测量方法之间发现了几乎相同的关系模式。
SCI-PAS的两个版本显示出相似的信度和效度特性。这表明该工具所挖掘的表型在美国和意大利的患者及对照人群中是一致的。
