Siddiqui M N, Zafar H, Alvi R, Ahmed M
Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Int J Clin Pract. 1998 Jun;52(4):265-7.
Magnesium is the second most abundant intracellular cation and the fourth most abundant cation in the body. Clinical manifestations of hypomagnesaemia include neuromusclar, neurological, psychiatric and cardiac arrhythmias including torsade de pointes resulting in sudden death. Incidence of hypomagnesaemia in hospitalised patients in common and there is a lack of clinical awareness. Clinicians should become familiar with the common conditions and therapeutics that are risk factors for underlying hypomagnesaemia and become familiar with magnesium replacement regimens. Two patients who suffered fatal complications in whom hypomagnesaemia was an important contributing factor are presented. Hypokalaemia and hypocalcaemia are common in severe magnesium deficiency and require concurrent monitoring and correcting.
镁是细胞内第二丰富的阳离子，也是体内第四丰富的阳离子。低镁血症的临床表现包括神经肌肉、神经、精神症状以及心律失常，包括尖端扭转型室速，可导致猝死。住院患者中低镁血症很常见，且临床认识不足。临床医生应熟悉作为潜在低镁血症危险因素的常见病症和治疗方法，并熟悉镁补充方案。本文介绍了两名发生致命并发症且低镁血症是重要促成因素的患者。低钾血症和低钙血症在严重镁缺乏时很常见，需要同时监测和纠正。
