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伴有低血糖的肝脏转移性恶性脑膜瘤:一例报告

Metastatic malignant meningioma of the liver with hypoglycemia: report of a case.

作者信息

Nabeya Y, Okazaki Y, Watanabe Y, Tohnosu N, Yamazaki M, Matsuda M, Iizuka H, Akutsu N, Kono T, Sato H, Kubosawa H

机构信息

Department of Surgery, Funabashi Municipal Medical Center, Chiba, Japan.

出版信息

Surg Today. 1998;28(9):953-8. doi: 10.1007/s005950050260.

Abstract

We herein present the case of a 68-year-old male who suffered an episode of hypoglycemic shock 2 years after undergoing total removal of a bifrontal parasagittal malignant meningioma. Imaging studies revealed three giant hypervascular tumors with a cystic portion in the right lobe, but no confirmed preoperative diagnosis could be made. At laparotomy, liver tumors were found in the medial segment of the left lobe as well as in the right lobe, and thus an extended right lobectomy was performed. All the resected tumors were histologically diagnosed as metastatic malignant meningiomas of the liver. Despite subsequent transarterial chemoembolization for a recurrence in the residual liver, the patient died 11 months after surgery. To the best of our knowledge, only one other case of a hepatectomy for liver metastases from an intracranial malignant meningioma has been reported in the literature, but there has never been any report of surgical treatment for a metastatic meningeal tumor in the liver associated with hypoglycemia. Although our surgical treatment provided effective palliation, the prognostic significance of a surgical strategy for such patients has yet to be established.

摘要

我们在此报告一例68岁男性患者,该患者在接受双额矢状旁恶性脑膜瘤全切术后2年发生了一次低血糖休克。影像学检查显示右叶有三个巨大的高血管性肿瘤,伴有囊性部分,但术前未得到确诊。在剖腹手术中,发现左叶内侧段以及右叶有肝肿瘤,因此进行了扩大右叶切除术。所有切除的肿瘤经组织学诊断为肝脏转移性恶性脑膜瘤。尽管随后对残留肝脏的复发灶进行了经动脉化疗栓塞,但患者在术后11个月死亡。据我们所知,文献中仅报道过另一例因颅内恶性脑膜瘤肝转移而行肝切除术的病例,但从未有过关于伴有低血糖的肝脏转移性脑膜瘤手术治疗的报道。尽管我们的手术治疗提供了有效的姑息治疗,但此类患者手术策略的预后意义尚未确立。

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