Machann J, Schick F, Seitz D, Lutz O, Claussen C D
Abteilung für Radiologische Diagnostik, Eberhard-Karls-Universität Tübingen.
Biomed Tech (Berl). 1998 Jul-Aug;43(7-8):202-9. doi: 10.1515/bmte.1998.43.7-8.202.
To assess trabecular density and structures at various cancellous bone sites in the foot using MR imaging. To compare the MRI findings with the bone mineral density (BMD) values obtained by quantitative computed tomography (QCT) in the lumbar vertebrae.
Bone mineral densities were measured by QCT in lumbar vertebrae 1 to 3 in ten patients with suspected osteoporosis. Sagittal images of the feet were obtained from these patients and also from seven healthy volunteers applying spin-echo and gradient-echo MR techniques.
MR imaging revealed differences between patients with osteoporosis and individuals with healthy bones. Comparison of MR and BMD data revealed a significant dependence of MR data on the bone density measured by QCT (alpha < 0.05). In addition, a good correlation (r = 0.73) was found between the results of the different MRI techniques.
The MR imaging techniques investigated offer an interesting tool for the non-invasive assessment of bony structures, at least at peripheral locations with yellow bone marrow. To enable reliable application in the clinical routine setting, additional studies are required to identify suitable standardized methods and establish normal ranges.
使用磁共振成像评估足部不同松质骨部位的小梁密度和结构。将磁共振成像结果与通过定量计算机断层扫描（QCT）获得的腰椎骨矿物质密度（BMD）值进行比较。
对10名疑似骨质疏松症患者的第1至3腰椎进行QCT测量骨矿物质密度。从这些患者以及7名健康志愿者身上获取足部矢状位图像，采用自旋回波和梯度回波磁共振技术。
磁共振成像显示骨质疏松症患者与健康骨骼个体之间存在差异。磁共振数据与BMD数据的比较显示，磁共振数据显著依赖于QCT测量的骨密度（α<0.05）。此外，不同磁共振成像技术的结果之间存在良好的相关性（r = 0.73）。
所研究的磁共振成像技术为骨结构的无创评估提供了一种有趣的工具，至少在含有黄骨髓的外周部位是如此。为了能够在临床常规环境中可靠应用，需要进一步研究以确定合适的标准化方法并建立正常范围。
