Verhaeghe I, Lafaut B A, Brandt A, De Laey J J
Department of Ophthalmology, University Hospital Gent.
Bull Soc Belge Ophtalmol. 1997;267:91-7.
The clinical manifestations of von Hippel and von Hippel-Lindau's disease are illustrated. Four cases are presented with special emphasis on the angiographic characteristics, the evolution and the complications of the retinal capillary hemangiomas. Special attention is given to fundoscopy, fluorescein and indocyanine green angiography and to the systemic manifestations. We summarize new molecular genetic insights. The importance of systemic and familial evaluation is stressed. Retinal angiomatosis is a clinical diagnosis but the angiography has an adjuvant value.
阐述了冯·希佩尔病和冯·希佩尔-林道病的临床表现。报告了4例病例，特别强调了视网膜毛细血管瘤的血管造影特征、发展过程及并发症。重点关注眼底镜检查、荧光素和吲哚菁绿血管造影以及全身表现。我们总结了新的分子遗传学见解。强调了全身和家族评估的重要性。视网膜血管瘤病是一种临床诊断，但血管造影具有辅助价值。
