Malvano R, Chiecchio A, Borsa M, Messeri G
PROMM, Ospedale Mauriziano, Torino, Italy.
Clin Chem Lab Med. 1998 Jun;36(7):463-8. doi: 10.1515/CCLM.1998.078.
The uncertainty associated with predictive value of test results was taken into consideration, as concerns both sampling error (related to the size of the statistical reference samples) and analytical imprecision (unavoidably involved by the measurement itself). A software package, developed for the statistical calculations, was used for the treatment of the results obtained for serum free thyroxin in euthyroid and dysthyroid subjects, assumed as an experimental model. Examples are shown for the obtainable functions predictive value vs. estimate and the related uncertainty regions. These data could help in comparing test results and, in particular, in preparing fully informative laboratory reports. The difficulties involved by an extensive application of the procedure are discussed.
考虑到与检测结果预测值相关的不确定性，这涉及抽样误差（与统计参考样本的大小有关）和分析不精密度（测量本身不可避免地存在）。一个为统计计算而开发的软件包被用于处理甲状腺功能正常和甲状腺功能异常受试者血清游离甲状腺素的检测结果，将其作为一个实验模型。给出了可获得的预测值与估计值函数以及相关不确定区域的示例。这些数据有助于比较检测结果，特别是有助于编制内容完整的实验室报告。讨论了该程序广泛应用所涉及的困难。
