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神经性厌食症和贪食症治疗的新进展有哪些?

What's New in the Treatment of Anorexia Nervosa and Bulimia?

作者信息

Sobel SV

机构信息

Private Practice in San Diego, Calif.

出版信息

Medscape Womens Health. 1996 Sep;1(9):5.

PMID:9746643
Abstract

The 3 eating disorders--anorexia nervosa, bulimia nervosa, and binge eating--occur at a frequency far greater than usually realized. Anorexia has been found to be present in up to 1% of teenage and young adult women, whereas estimates of bulimia have ranged up to 5%. The prevalence of binge-eating disorder is not known, but may be higher than bulimia. Anorexia nervosa is characterized by weight loss, body image disturbance, and a morbid fear of weight gain. Bulimia nervosa is characterized by binge eating and compensatory purging by vomiting; use of laxatives, diuretics, or diet pills; exercise; or fasting. Binge-eating disorder is characterized by binge behavior and loss of control of food intake, with an absence of purging. Eating disorders create significant mortality and morbidity. Medical complications associated with anorexia are those related to malnutrition and semistarvation. Medical complications associated with bulimia are those related to electrolyte imbalance and the physical effects of vomiting. The mortality rate of eating disorders may be as high as 15%, including deaths from arrhythmia, gastric hemorrhaging, and suicide. The core struggle within women with anorexia is the "2 Ps": feeling powerless and striving towards perfectionism. The core conflict within a bulimic person appears to be the "2 Ds": deprivation and dependency. The treatment of eating disorders includes psychotherapy, and, frequently, psychopharmacologic intervention. The psychotherapy primarily addresses issues of chaotic eating, hunger, inadequate caloric intake, conditioned response, and profound fear of expressing impulses and feelings, especially those of anger and sadness. Antidepressants, especially serotonergic agents, have been found to be useful, particularly in the treatment of bulimia.

摘要

三种饮食失调症——神经性厌食症、神经性贪食症和暴饮暴食症——的发生频率远远高于通常的认知。据发现,神经性厌食症在青少年和年轻成年女性中的发病率高达1%,而神经性贪食症的估计发病率则高达5%。暴饮暴食症的患病率尚不清楚,但可能高于神经性贪食症。神经性厌食症的特征是体重减轻、身体形象紊乱以及对体重增加的病态恐惧。神经性贪食症的特征是暴饮暴食以及通过呕吐进行代偿性清除;使用泻药、利尿剂或减肥药;运动;或禁食。暴饮暴食症的特征是暴饮暴食行为和食物摄入失控,且没有清除行为。饮食失调症会导致严重的死亡率和发病率。与神经性厌食症相关的医学并发症是那些与营养不良和半饥饿有关的并发症。与神经性贪食症相关的医学并发症是那些与电解质失衡以及呕吐的身体影响有关的并发症。饮食失调症的死亡率可能高达15%,包括心律失常、胃出血和自杀导致的死亡。患有神经性厌食症的女性内心的核心挣扎是“两个P”:感到无力和追求完美主义。患有神经性贪食症的人内心的核心冲突似乎是“两个D”:剥夺和依赖。饮食失调症的治疗包括心理治疗,而且通常还包括心理药物干预。心理治疗主要解决饮食混乱、饥饿、热量摄入不足、条件反应以及对表达冲动和情感,尤其是愤怒和悲伤情感的深深恐惧等问题。抗抑郁药,尤其是血清素能药物,已被发现是有用的,特别是在治疗神经性贪食症方面。

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