Kim W, Shin D J, You S A, Kim Y J
Department of Biology, Dankook University, Republic of Korea.
J Hum Genet. 1998;43(3):195-8. doi: 10.1007/s100380050069.
The Y Alu polymorphic (YAP) element (DYS287) and the Y-linked tetranucleotide microsatellite locus DYS19 were examined in samples from a total of 455 unrelated males in the Korean population. The frequency of the YAP allele was found to be 1.3% (6/455) in the Korean population. These results are consistent with previous reports that showed the YAP element to be absent in most Asian populations, with the exception of the high frequency of the YAP allele in the Japanese population. All five common alleles at the DYS19 locus were identified in this study, The C allele was the most frequent (197/455), followed by the D (119/455), B (78/455), E (41/455), and A (20/455) alleles. Seven combination haplotypes (DYS287/DYS19) were found, and the mean combination haplotype diversity in the Korean population appeared to be 0.71. Based on results of these two loci, Japanese and Korean populations may share some common genetic structure that could reflect recent gene flow and some amount of admixture of Y chromosomes between these two populations.
在韩国人群中，对455名无亲缘关系男性的样本检测了Y染色体Alu多态性（YAP）元件（DYS287）和Y连锁四核苷酸微卫星位点DYS19。韩国人群中YAP等位基因频率为1.3%（6/455）。这些结果与之前的报告一致，即大多数亚洲人群中不存在YAP元件，日本人群中YAP等位基因频率较高除外。本研究鉴定出了DYS19位点的所有五个常见等位基因，C等位基因最常见（197/455），其次是D（119/455）、B（78/455）、E（41/455）和A（20/455）等位基因。发现了七种组合单倍型（DYS287/DYS19），韩国人群中的平均组合单倍型多样性似乎为0.71。基于这两个位点的结果，日本和韩国人群可能共享一些共同的遗传结构，这可能反映了最近的基因流动以及这两个人群之间Y染色体的一定程度混合。
