Skinner S, Naqvi M, Biskinis E K
Department of Medicine/Pediatrics, Maricopa Medical Center, Phoenix, Ariz., USA.
Tex Med. 1998 Sep;94(9):57-8.
Apnea in the neonatal period frequently is associated with prematurity. Full-term infants who develop apnea usually have associated clinical conditions such as infection, shock, metabolic disorders, neonatal abstinence syndrome, intracranial pathology, and gastroesophageal reflux. Gastric ulcer also is a rare phenomenon in the neonatal period. We describe a full-term infant presenting with apnea. Upon investigation, a 6-channel pneumocardiogram revealed central apnea and multiple episodes of low esophageal pH (< 4), which is suggestive of gastroesophageal reflux. This was confirmed by an upper gastrointestinal series. A small antral ulcer crater also was demonstrated. When assessing the etiology of apnea in a full-term infant, gastroesophageal reflux and gastric ulcer should be considered.
新生儿期的呼吸暂停常与早产有关。发生呼吸暂停的足月儿通常伴有感染、休克、代谢紊乱、新生儿戒断综合征、颅内病变和胃食管反流等临床情况。胃溃疡在新生儿期也是一种罕见现象。我们描述了一名出现呼吸暂停的足月儿。经检查，六通道心电图显示中枢性呼吸暂停和多次食管下段pH值低（<4），提示胃食管反流。上消化道造影证实了这一点。还发现了一个小的胃窦溃疡龛影。在评估足月儿呼吸暂停的病因时，应考虑胃食管反流和胃溃疡。
