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兔隔区损伤后的情绪过度反应和强直性静止增强

Hyperemotionality and enhanced tonic immobility after septal lesions in the rabbit.

作者信息

Woodruff M L, Lippincott W I

出版信息

Brain Behav Evol. 1976;13(1):22-33. doi: 10.1159/000123799.

DOI:10.1159/000123799
PMID:974721
Abstract

Large lesions of the septal region in the rabbit increased tonic immobility as measured by the number of successful inductions and by duration of immobility. Open field activity was also increased. Septally lesioned rabbits also exhibited increased emotionality, although the topography of the 'septal syndrome' in these rabbits was different from that described for rats. The septally lesioned rabbits exhibited increases in fear reactions such as thumping, escape responses and vocalization when caught, rather than increased aggressiveness. The results are discussed in terms of loss of inhibition of species-typical responses after septal damage.

摘要

通过成功诱导的次数和静止不动的持续时间来衡量,兔中隔区域的大损伤会增加紧张性不动。旷场活动也会增加。中隔损伤的兔还表现出情绪增强,尽管这些兔中“中隔综合征”的表现形式与大鼠中描述的不同。中隔损伤的兔在被抓住时表现出恐惧反应增加,如跺脚、逃避反应和鸣叫,而不是攻击性增强。根据中隔损伤后物种典型反应抑制的丧失来讨论这些结果。

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