Kourda M, Krichen H, Kennou H, Ben Yahia K, Ben Ayed M, Souissi R
Service de Dermatologie, EPS Habib Thameur, Tunis, Tunisie.
Ann Dermatol Venereol. 1998 Apr;125(4):255-6.
Giant cell fibroblastoma is a rare mesenchyma tumor of childhood having many similarities with dermatofibrosarcoma protuberans in adults.
We report the case of a 28-year-old woman presenting a subcutaneous inter-mammary mass associating both tumors. Immunohistochemistry showed an expression of CD 34 only by dermatofibrosarcoma protuberans cells.
It is important to stress: the rarity of this association, the difficulty to confirm the diagnosis and to establish the links between these two tumors: simple association (as in our case), transformation or recurrence of giant cell fibroblastoma in dermatofibrosarcoma protuberans.
巨细胞纤维母细胞瘤是一种罕见的儿童间充质肿瘤，与成人的隆突性皮肤纤维肉瘤有许多相似之处。
我们报告了一例28岁女性病例，其乳房间皮下肿物同时存在这两种肿瘤。免疫组化显示仅隆突性皮肤纤维肉瘤细胞表达CD 34。
必须强调的是：这种关联罕见，难以确诊以及确定这两种肿瘤之间的联系：单纯关联（如我们的病例）、巨细胞纤维母细胞瘤转变为隆突性皮肤纤维肉瘤或隆突性皮肤纤维肉瘤复发。
