Anzai H, Kikuchi A, Kinoshita A, Nishikawa T
Department of Dermatology, Keio University, School of Medicine, Tokyo, Japan.
Br J Dermatol. 1998 Jun;138(6):1058-60. doi: 10.1046/j.1365-2133.1998.02279.x.
Juvenile chronic myelogenous leukaemia (JCML) is a rare haematological malignancy of myelomonocytic lineage that affects patients less than 4 years of age and is known as an entity different from adult-type chronic myelogenous leukaemia. In JCML, skin manifestations are relatively common but most of them have been reported as a non-specific eruption, which histologically may show changes resembling neurofibromatosis or xanthogranuloma. We present a 2-year-old boy with JCML who developed a recurrent annular erythema in which leukaemic infiltrates were confirmed histologically, even though his bone marrow examination suggested that be remained in haematological remission.
