Bosworth C F, Sample P A, Gupta N, Bathija R, Weinreb R N
Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla 92093-0946, USA.
Arch Ophthalmol. 1998 Sep;116(9):1153-8. doi: 10.1001/archopht.116.9.1153.
To determine if motion automated perimetry can identify early glaucomatous visual field defects in patients with suspected glaucoma (by disc), those with ocular hypertension, and those with primary open-angle glaucoma.
Motion automated perimetry, a foveally centered motion test, and standard visual field tests were conducted on one randomly selected eye of normal patients (n = 38), patients with suspected glaucoma (by disc) (n = 28), patients with ocular hypertension (n = 18), and patients with primary open-angle glaucoma (n = 21). Subjects' performance on both motion tests were compared with their performance on standard perimetry.
Perimetric motion thresholds significantly distinguished the groups (P< or =.001), while the foveally centered motion test was unable to separate them (P< or =.32). Of the total patients, 90.5% of those with glaucoma, 39.3% of those with suspected glaucoma, 27.8% of those with ocular hypertension, and 5.3% of the normal subjects had abnormal results on motion automated perimetry testing. Perimetric motion thresholds were significantly correlated with standard visual field thresholds (P< or =.001).
Motion automated perimetry identifies visual field defects in patients who already show standard visual field loss as well as in a moderate percentage of those with suspected glaucoma and ocular hypertension, indicating that the testing of discrete locations might be necessary for increased diagnostic utility.
确定动态自动视野检查能否识别疑似青光眼(基于视盘)患者、高眼压症患者和原发性开角型青光眼患者的早期青光眼性视野缺损。
对正常患者(n = 38)、疑似青光眼(基于视盘)患者(n = 28)、高眼压症患者(n = 18)和原发性开角型青光眼患者(n = 21)的一只随机选择的眼睛进行动态自动视野检查、以黄斑为中心的动态测试和标准视野检查。将受试者在两种动态测试中的表现与其在标准视野检查中的表现进行比较。
视野动态阈值能显著区分不同组(P≤0.001),而以黄斑为中心的动态测试无法区分(P≤0.32)。在所有患者中,青光眼患者中有90.5%、疑似青光眼患者中有39.3%、高眼压症患者中有27.8%以及正常受试者中有5.3%在动态自动视野检查中结果异常。视野动态阈值与标准视野阈值显著相关(P≤0.001)。
动态自动视野检查能识别已出现标准视野缺损的患者以及相当比例的疑似青光眼和高眼压症患者的视野缺损,这表明为提高诊断效用,可能需要对离散位置进行检测。