Sample P A, Bosworth C F, Weinreb R N
Glaucoma Center, University of California, San Diego, La Jolla, USA.
Arch Ophthalmol. 1997 Sep;115(9):1129-33. doi: 10.1001/archopht.1997.01100160299006.
To compare short-wavelength automated perimetry (SWAP), a test favoring the detection of the target by the parvocellular pathways of vision, with motion automated perimetry (MAP), a test favoring detection by the magnocellular pathways, in the same eyes.
Thirty-three individuals in whom glaucoma was suspected (glaucoma suspects) and 17 patients with primary open-angle glaucoma were compared with 30 age-matched normal control subjects.
Short-wavelength automated perimetry was done with the usual protocol (program 24-2). Motion coherence thresholds were measured with 14 random do targets that covered the 24-2 field area. Short-wavelength automated perimetry test locations corresponding to each of the 14 motion automated perimetry locations were averaged to compare 14 locations for each text.
Short-wavelength automated perimetry and motion automated perimetry were correlated by visual field location (whole field r = -0.40, P < .001), especially in the superior field (r = -0.45, P < .001). Overlap for defective locations was present in 16 (94%) of the 17 eyes with glaucoma, although in the glaucoma suspect eyes each test showed the earliest deficit in a percentage of individuals with overlap in only 3 (21%) of the 14 eyes. An analysis of variance showed a significant effect of diagnosis for both tests (SWAP and MAP, P < .001); the eyes of patients with glaucoma were significantly different from those of the normal controls. The results for glaucoma suspects were significantly different on SWAP only in the superior temporal field (Tukey-Kramer test).
Both tests successfully identified eyes with glaucoma and a percentage of the glaucoma suspect eyes; both were correlated by field location. These results suggest that damage due to glaucoma is nonselective for either the parvocellular or the magnocellular ganglion cell axons, that there may be individual differences in which type of ganglion cell shows damage first, and that when standard visual field loss is present the results of SWAP and MAP are defective.
在同一只眼睛中，比较短波长自动视野计（SWAP）（一种有利于通过视觉的小细胞通路检测目标的测试）和运动自动视野计（MAP）（一种有利于通过大细胞通路检测目标的测试）。
将33名疑似青光眼患者（青光眼可疑者）和17名原发性开角型青光眼患者与30名年龄匹配的正常对照受试者进行比较。
采用常规方案（程序24-2）进行短波长自动视野计检查。用14个随机点目标测量运动相干阈值，这些目标覆盖24-2视野区域。将与14个运动自动视野计位置相对应的短波长自动视野计测试位置进行平均，以比较每种测试的14个位置。
短波长自动视野计和运动自动视野计在视野位置上具有相关性（全视野r = -0.40，P <.001），尤其是在上半视野（r = -0.45，P <.001）。17只青光眼眼中有16只（94%）存在缺陷位置的重叠，尽管在青光眼可疑者眼中，每种测试仅在14只眼中的3只（21%）有重叠的个体中显示出最早的缺陷。方差分析显示两种测试（SWAP和MAP，P <.001）的诊断均有显著影响；青光眼患者的眼睛与正常对照者的眼睛有显著差异。仅在颞上半视野，青光眼可疑者在SWAP测试中的结果有显著差异（Tukey-Kramer检验）。
两种测试均成功识别出青光眼患者的眼睛以及一定比例的青光眼可疑者的眼睛；两者在视野位置上具有相关性。这些结果表明，青光眼造成的损害对小细胞或大细胞神经节细胞轴突并无选择性，可能存在个体差异，即哪种类型的神经节细胞首先出现损害，并且当出现标准视野缺损时，SWAP和MAP的结果均有缺陷。
