Hutchinson S J, Goldberg D J, Gore S M, Cameron S, McGregor J, McMenamin J, McGavigan J
MRC Biostatistics Initiative for AIDS and HIV in Scotland, Centre for HIV Research, Edinburgh.
Epidemiol Infect. 1998 Aug;121(1):185-91. doi: 10.1017/s0950268898001022.
This data linkage study examined the extent of hepatitis B transmission and co-infection with HIV among 636 former inmates of Glenochil prison, Scotland, during an outbreak of bloodborne diseases in 1993 which was related to needle sharing. Eleven inmates imprisoned during the first half of 1993 presented with hepatitis B infection, of whom co-infection with HIV was detected in six. Based on dates of test results in relation to time of imprisonment, seven definitely acquired their hepatitis B infection within the prison. Only two infections were reported to Scotland's hepatitis B register and neither could be prison-linked. This outbreak of hepatitis B is the first of its kind to be reported but not the first to have occurred. It not only highlights the urgency for measures to prevent further spread of infection among prisoners but also illustrates the need for comprehensive surveillance of hepatitis B infection, and the need for a protocol on how to manage such outbreaks and on how to establish the extent of transmissions when acute hepatitis B occurs in prison.
这项数据关联研究调查了1993年苏格兰格莱诺基尔监狱636名前囚犯中乙肝传播及与艾滋病毒合并感染的情况,当时该监狱爆发了与共用针头有关的血源性病原体疾病。1993年上半年被监禁的11名囚犯出现乙肝感染,其中6人检测出与艾滋病毒合并感染。根据检测结果日期与监禁时间的关系,7人肯定是在监狱内感染了乙肝。只有两例感染报告给了苏格兰乙肝登记处,但均无法确定与监狱有关。此次乙肝疫情是首次报告此类情况,但并非首例发生。它不仅凸显了采取措施防止感染在囚犯中进一步传播的紧迫性,还说明了对乙肝感染进行全面监测的必要性,以及制定应对此类疫情及监狱中出现急性乙肝时如何确定传播范围的方案的必要性。