Chen X M, Hosono T, Mizuno A, Yoda T, Yoshida K, Aoyagi Y, Kanosue K
Department of Physiology, School of Allied Health Sciences, Osaka University Faculty of Medicine, Suita, Japan.
Physiol Behav. 1998 Jun 1;64(3):419-24. doi: 10.1016/s0031-9384(98)00094-8.
The operant system described here contains a box that can be convectively heated or cooled. A rat moves freely in the box. Its location is monitored photoelectrically while its deep body temperature is monitored by a telemetry system. In heat-escape experiments, hot air (40 degrees C) flows through the box. When the rat enters a reward zone the air source is switched and cold air (0 degrees C) flows through the box for a given period (30 s). Conversely, in cold-escape experiments cold air flows through the box and when the rat enters the reward zone the air source is switched to a warm one. Experiments show that rats quickly learn to stay near the reward zone and move in and out of it periodically. This system is based on behavior more natural than the frequently used lever-pressing response, and has many advantages for use in studies involving behavioral thermoregulation.
这里描述的操作性系统包含一个可以进行对流加热或冷却的箱子。一只大鼠在箱子里自由活动。通过光电方式监测其位置，同时通过遥测系统监测其深部体温。在热逃避实验中，热空气（40摄氏度）流经箱子。当大鼠进入奖励区域时，空气源切换，冷空气（0摄氏度）在给定时间段（30秒）内流经箱子。相反，在冷逃避实验中，冷空气流经箱子，当大鼠进入奖励区域时，空气源切换为热空气。实验表明，大鼠很快学会待在奖励区域附近，并周期性地进出该区域。该系统基于比常用的按压杠杆反应更自然的行为，在涉及行为体温调节的研究中有许多优势。
