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配子识别蛋白的进化。

Evolution of gamete recognition proteins.

作者信息

Vacquier V D

机构信息

Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093-0202, USA.

出版信息

Science. 1998 Sep 25;281(5385):1995-8. doi: 10.1126/science.281.5385.1995.

DOI:10.1126/science.281.5385.1995
PMID:9748153
Abstract

REVIEW Although fertilization has been studied for more than a century, the cell surface proteins mediating the process are only now becoming known. Gamete interaction in animals appears to be molecularly complex. Although it is difficult to generalize at present, diversity of structure may be a recurring theme in the evolution of fertilization proteins. Examples of rapid evolution of fertilization proteins by positive selection are known, and concerted evolution can influence the differentiation of gamete recognition proteins between closely related species.

摘要

综述 尽管受精过程已被研究了一个多世纪,但介导这一过程的细胞表面蛋白直到现在才为人所知。动物中的配子相互作用在分子层面似乎很复杂。虽然目前很难一概而论,但结构多样性可能是受精蛋白进化过程中反复出现的一个主题。通过正选择实现受精蛋白快速进化的例子是已知的,并且协同进化会影响亲缘关系较近物种之间配子识别蛋白的分化。

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