Jílek D, Král V, Duchková H, Richter J
Imunologický odbor Krajské hygienické stanice v Ustí n. L.
Cas Lek Cesk. 1998 Jun 29;137(13):397-9.
In the submitted review the authors present information on possibilities of immunomodulating treatment of atopic dermatitis. Immunosuppressive treatment comprises systemic corticosteroid administration (possibly combined with cytostatic immunosuppressive preparations), cyclosporin A and phototherapy. Immunopotentiating treatment of AD makes use mainly of modulating preparations with the nature of physiological substances close to the immune system, substances obtained from natural biological sources (thymic hormones) or in recent years more frequently substances of recombinant origin (interferons, interleukins). The use of immunopotentiating drugs of chemical origin (synthetic substances) is used less frequently in AD. The use of intravenous immunoglobulin preparations for severe forms of atopic dermatitis is only just starting.
在提交的综述中,作者介绍了特应性皮炎免疫调节治疗的可能性。免疫抑制治疗包括全身使用皮质类固醇(可能与细胞抑制性免疫抑制制剂联合使用)、环孢素A和光疗。特应性皮炎的免疫增强治疗主要利用与免疫系统性质相近的生理物质调节剂、从天然生物来源获得的物质(胸腺激素),或者近年来更常用的重组来源物质(干扰素、白细胞介素)。化学合成来源的免疫增强药物在特应性皮炎中的使用较少。静脉注射免疫球蛋白制剂用于重度特应性皮炎的治疗才刚刚起步。