Pua Vernon S C, Barnetson Ross StC
Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Australas J Dermatol. 2006 May;47(2):84-9. doi: 10.1111/j.1440-0960.2006.00237.x.
Atopic dermatitis is a common inflammatory skin condition with increasing incidence in recent decades. The mainstay of treatment has been the combination of emollients and topical corticosteroids, with the addition of systemic therapies in severe cases. New drugs such as the topical calcineurin inhibitors have shown promise in treating mild-to-severe atopic dermatitis. Other novel therapies that have been reported in the literature include leukotriene antagonists, monoclonal antibodies such as infliximab, leflunomide, recombinant interferon gamma and intravenous immunoglobulin. This review will focus on the treatment of adult atopic dermatitis.
特应性皮炎是一种常见的炎症性皮肤病，近几十年来发病率不断上升。治疗的主要方法一直是润肤剂和外用皮质类固醇的联合使用，严重病例还需加用全身治疗。新型药物如外用钙调神经磷酸酶抑制剂在治疗轻至重度特应性皮炎方面已显示出前景。文献中报道的其他新型疗法包括白三烯拮抗剂、英夫利昔单抗等单克隆抗体、来氟米特、重组干扰素γ和静脉注射免疫球蛋白。本综述将聚焦于成人特应性皮炎的治疗。
