Manens J P, Buchheit I, Beauvais H, Gaboriaud G, Mazal A, Piret P
Département des radiations, Centre Eugène-Marquis, Rennes, France.
Cancer Radiother. 1998 Mar-Apr;2(2):105-14. doi: 10.1016/s1278-3218(98)89081-1.
A high performance standard radiotherapy treatment unit could be used to perform stereotactic radiosurgery. The dosimetric aspects of stereotactic irradiation with small size photon beams (energies from 5 to 25 MV produced by electron linear accelerator or gamma-rays produced by cobalt-60 treatment unit) are analyzed. The diameter of circular beams used are 5 to 40 millimeters wide at the isocenter of the treatment unit. The dosimetry of small x-ray fields is complicated by two factors: the relationship between detector size and field size dimensions, and the lack of lateral electron equilibrium. The large dose gradients outside the beam's central axis require dosimetry techniques with higher spatial resolution. To determine the best dosimetry system for measurements at the beam's small focal point, particularly for measurement of the field size dependent on output factors, several different detectors were investigated: ionization chamber, silicon diode, diamond detector, thermoluminescent dosimeter, and film. Ionization chamber, which presents a sensitive volume smaller than 0.02 cm3, is the most commonly recommended detector for field diameter above 8 mm. Current representative examples of dosimetric measurements for different x-ray energies, including percent depth dose, tissue maximum ratios, beam profiles (off axis ratios), and output factors, are presented and discussed. As well, the dosimetric characteristics of small photon beams are detailed.
一台高性能标准放射治疗设备可用于实施立体定向放射外科手术。分析了使用小尺寸光子束(电子直线加速器产生的5至25兆电子伏特能量的射线或钴 - 60治疗设备产生的伽马射线)进行立体定向照射的剂量学方面。所使用的圆形束在治疗设备等中心处的直径为5至40毫米宽。小X射线野的剂量学因两个因素而变得复杂:探测器尺寸与野尺寸之间的关系,以及缺乏横向电子平衡。束中心轴外的大剂量梯度需要具有更高空间分辨率的剂量学技术。为了确定用于在束的小焦点处进行测量的最佳剂量学系统,特别是用于测量与输出因子相关的野尺寸,研究了几种不同的探测器:电离室、硅二极管、金刚石探测器、热释光剂量计和胶片。电离室的灵敏体积小于0.02立方厘米,是对于直径大于8毫米的野最常推荐的探测器。给出并讨论了不同X射线能量剂量学测量的当前代表性示例,包括百分深度剂量、组织最大剂量比、束剖面(离轴比)和输出因子。此外,还详细介绍了小光子束的剂量学特性。