Vernier I, Amar J, Ruidavets J B, Ferrieres J, Chamontin B
Service d'épuration extrarénale et de néphrologie.
Arch Mal Coeur Vaiss. 1998 Aug;91(8):1055-7.
1,160 subjects aged 35-64 years were recruited by the Haute-Garonne MONICA center, and selected by stratified randomization on age and size of home area. The hypertensive group included: 176 subjects newly diagnosed as hypertensives (blood pressure > or = 140/90 mmHg), 86 known but untreated hypertensives and 178 hypertensives under treatment. For each subject a score of coronary heart disease risk based on the Framingham point score probability algorithm was calculated. The prevalence of hypertension was 37.9%. Among the 440 subjects considered as hypertensives, 60% were aware of having hypertension. Only 30% of the 178 patients treated achieved blood pressure control. The population as a whole was at low coronary heart disease risk (< 5% at 10 years); the groups at higher risk were newly diagnosed hypertensives and treated hypertensives. Among known hypertensives, the risk level was higher in treated compared with untreated. In this survey 1) the prevalence of hypertension was high; 2) only 30% of treated hypertensives were below 140/90 mmHg; 3) usual care failed to recognize 40% of hypertensives at same risk level as treated ones; 4) treated hypertensives had higher coronary heart disease risk than untreated known hypertensives. The hypertension therapeutic strategy could be based on the reduction of blood pressure below the threshold 140/90 mmHg rather than on the absolute cardiovascular risk.
上加龙省莫尼卡中心招募了1160名年龄在35至64岁之间的受试者,并根据年龄和家庭所在地区规模进行分层随机抽样。高血压组包括:176名新诊断为高血压的受试者(血压≥140/90 mmHg)、86名已知患有高血压但未接受治疗的受试者以及178名正在接受治疗的高血压患者。为每位受试者根据弗雷明汉评分概率算法计算冠心病风险得分。高血压患病率为37.9%。在被视为高血压患者的440名受试者中,60%知晓自己患有高血压。在178名接受治疗的患者中,只有30%的患者血压得到控制。总体人群患冠心病的风险较低(10年内<5%);风险较高的群体是新诊断出的高血压患者和接受治疗的高血压患者。在已知患有高血压的人群中,接受治疗者的风险水平高于未接受治疗者。在本次调查中:1)高血压患病率较高;2)只有30%接受治疗的高血压患者血压低于140/90 mmHg;3)常规护理未能识别出40%与接受治疗的患者处于相同风险水平的高血压患者;4)接受治疗的高血压患者患冠心病的风险高于已知未接受治疗的高血压患者。高血压治疗策略可基于将血压降至140/90 mmHg以下的阈值,而非基于绝对心血管风险。