Piquemal R, Fauchier L, Regimbeau C, Babuty D, Neville P, Renard J P
Service de médecine interne A, Tours.
Arch Mal Coeur Vaiss. 1998 Jul;91(7):879-81.
The authors report the cases of two patients admitted to hospital for investigation of haemolytic anaemia. Both had undergone, 10 and 12 years previously, mitral valve replacement with a Ionescu-Shiley bioprosthesis. In both cases, in the absence of signs of cardiac failure, Doppler echocardiography showed mitral regurgitation. The association of haemolytic anaemia and dysfunction of the bioprosthesis led to redux valve replacement and correction of the anaemia. Haemolytic anaemia was the presenting sign of bioprosthetic valve dysfunction requiring replacement of the prosthesis. This complication is common with mechanical valve prostheses but much more rare in bioprosthetic valves.
作者报告了两名因溶血性贫血入院检查的患者病例。两人分别在10年前和12年前接受了用Ionescu-Shiley生物瓣膜进行的二尖瓣置换术。在这两个病例中，在没有心力衰竭迹象的情况下，多普勒超声心动图显示二尖瓣反流。溶血性贫血与生物瓣膜功能障碍相关，导致再次进行瓣膜置换并纠正贫血。溶血性贫血是生物瓣膜功能障碍需要更换瓣膜的首发症状。这种并发症在机械瓣膜置换术中很常见，但在生物瓣膜中则更为罕见。
