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[心脏移植术后可逆性移植物功能障碍]

[Reversible graft dysfunction after cardiac transplantation].

作者信息

Obadia J F, Boissonnat P, Bastien O, Flamens C, Martelloni Y, Diab C, Elfarra M, Chassignolle J F, Dureau G

机构信息

Service de chirurgie cardio-thoracique A, Hôpital cardiologique, Lyon.

出版信息

Arch Mal Coeur Vaiss. 1998 Feb;91(2):253-6.

PMID:9749253
Abstract

The authors report 3 cases of major graft dysfunction after cardiac transplantation which recovered completely with biventricular mechanical assistance in 4 to 8 days. All three cases were primary biventricular graft failures in patients with normal preoperative pulmonary resistances. These early dysfunctions (with no signs of myocardial infarction on electro- or echocardiography and in the absence of abnormal increased peri-operative enzyme levels) associated with total functional recovery conforming to the definition of the phenomenon of myocardial stunning. These results argue in favour of aggressive management of primary graft dysfunction.

摘要

作者报告了3例心脏移植后发生严重移植物功能障碍的病例,这些病例在接受双心室机械辅助4至8天后完全恢复。所有3例均为术前肺阻力正常患者的原发性双心室移植物衰竭。这些早期功能障碍(心电图或超声心动图上无心肌梗死迹象,围手术期酶水平无异常升高)与完全功能恢复相关,符合心肌顿抑现象的定义。这些结果支持对原发性移植物功能障碍进行积极处理。

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