Altukhov Iu P
Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Genetika. 1998 Jul;34(7):908-19.
Humans, animals, and plants are shown to have a universal polygenic system maintained by stabilizing selection, which underlies highly significant correlations between multilocus allozyme heterozygosity, the sexual maturation rate, and longevity. For 77 animal and 30 plant species, it was demonstrated that allozyme genomic heterozygosity (1) is positively correlated with rate of sexual maturity (2) (r12 = 0.815, P < 0.001) and negatively correlated with longevity; (3) (r13 = -0.793, P < 0.001). These relationships are significantly affected by the genotype-environment interactions that modify the structure of the metabolism related to growth and development. An increase in the number of heterotic genes involved in growth and development increases the energy expenditure in this ontogenetic period, accelerates the sexual maturation rate, and shortens the life span.
人类、动物和植物都显示出具有一个由稳定选择维持的通用多基因系统，这是多位点等位酶杂合性、性成熟率和寿命之间高度显著相关性的基础。对于77种动物和30种植物物种，已证明等位酶基因组杂合性：（1）与性成熟率呈正相关（2）（r12 = 0.815，P < 0.001），与寿命呈负相关；（3）（r13 = -0.793，P < 0.001）。这些关系受到基因型 - 环境相互作用的显著影响，这种相互作用会改变与生长和发育相关的代谢结构。参与生长和发育的杂种优势基因数量增加会增加这个个体发育时期的能量消耗，加速性成熟率，并缩短寿命。
