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[个体对紫外线辐射敏感性的因素]

[The factors of individual sensitivity to ultraviolet radiation].

作者信息

Strzhizhovskiĭ A D

机构信息

State Research Centre of RF, Institute of Biomedical Problems, Moscow.

出版信息

Usp Fiziol Nauk. 1998 Jul-Sep;29(3):130-43.

PMID:9749462
Abstract

Correlations between effective UVR doses for induction of skin erythema, premature aging and cancer, immunosuppression, vitamin D photobiosynthesis and cataract on the one hand and various ethnic signs, sex, age and metabolic states of organism on the other were considered. Individual UV sensitivity by all criteria mentioned with the exception of immunosuppression and cataract is conditioned by specificity of melanin and DNA metabolism, and risk of skin cancer incidence besides that depends of immune system state. Values of risk factors for UVR effects mentioned incidence in individuals of different sex and age with various ethnic and metabolic conditions are presented.

摘要

一方面考虑了诱导皮肤红斑、过早衰老和癌症、免疫抑制、维生素D光生物合成以及白内障的有效紫外线辐射剂量与另一方面各种种族特征、性别、年龄和机体代谢状态之间的相关性。除免疫抑制和白内障外,所有提及标准下的个体紫外线敏感性均由黑色素和DNA代谢的特异性决定,此外皮肤癌发病风险还取决于免疫系统状态。给出了不同性别和年龄、具有各种种族和代谢状况个体中提及的紫外线辐射效应风险因素发生率的值。

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