Dreyer G, Santos A, Noroes J, Amaral F, Addiss D
Departamento de Parasitologia, Centro de Pesquisas Aggeu Magalhaes-FIOCRUZ, Recife, PE, Brazil.
Am J Trop Med Hyg. 1998 Sep;59(3):399-403. doi: 10.4269/ajtmh.1998.59.399.
Adult Wuchereria bancrofti can be readily detected by ultrasound in the lymphatic vessels of the spermatic cord with a 7.5-MHz transducer, but most ultrasound machines in developing countries are equipped with 3.5-MHz transducers. To assess the potential for ultrasound as a tool for diagnosis and epidemiologic assessment in lymphatic filariasis, we compared the performance of 3.5-MHz and 7.5-MHz transducers in 61 men in Recife, Brazil. All men had three ultrasound examinations using a 3.5 MHz transducer and an examination with a 7.5-MHz probe. Using the 7.5-MHz transducer, adult W. bancrofti were detected in 41 men; 81 adult worm nests were detected. Sixty-four (79%) nests were detected with the 3.5-MHz probe, each on all three examinations. The 3.5-MHz probe correctly identified 35 (85.4%) of 41 men as infected; sensitivity increased with lymphatic vessel diameter. Ultrasonographic examination with a 3.5-MHz transducer is a sensitive method for detection of adult W. bancrofti in men and merits consideration as a tool for rapid epidemiologic assessment.
使用7.5兆赫的换能器，通过超声能够轻易在精索淋巴管中检测到成年班氏吴策线虫，但发展中国家的大多数超声设备配备的是3.5兆赫的换能器。为评估超声作为淋巴丝虫病诊断和流行病学评估工具的潜力，我们在巴西累西腓对61名男性进行了3.5兆赫和7.5兆赫换能器性能的比较。所有男性均使用3.5兆赫的换能器进行了三次超声检查，并使用7.5兆赫的探头进行了一次检查。使用7.5兆赫的换能器，在41名男性中检测到成年班氏吴策线虫；检测到81个成虫巢。使用3.5兆赫的探头，在所有三次检查中均检测到64个（79%）成虫巢。3.5兆赫的探头正确识别出41名男性中有35名（85.4%）受到感染；敏感性随淋巴管直径增加。使用3.5兆赫换能器进行超声检查是检测男性成年班氏吴策线虫的一种敏感方法，值得作为快速流行病学评估工具加以考虑。
