Podoba J, Hnilica P, Makaiová I, Kovác A
Subkatedra endokrinológie a metabolických chorôb Institútu pre d'alsie vzdelávanie pracovníkov v zdravotníctve, Bratislava.
Vnitr Lek. 1997 Sep;43(9):611-4.
Thyrotropin secreting pituitary adenomas are scarce. They may cause an extremely rare form of hyperthyroidism. The diagnosis is often delayed because the clinical symptoms are attributed to common types of hyperthyroidism. The diagnosis involves detection of elevated or normal (unsuppressed) thyrotropin levels in hyperthyroid patients and evidence of a pituitary adenoma by computed tomography or magnetic resonance imaging. The thyrotropin response in the thyrotropin-releasing hormone test is either absent or insufficient. When the pituitary microadenoma appears to be undetectable, the familiar syndrome of selective pituitary resistance to thyroid hormones has to be excluded. Treatment involves extirpation of the tumour. If the macroadenoma is not removed completely, external radiotherapy of the pituitary follows. If this conventional treatment does not produce an adequate effect, treatment with long-acting somatostatin analogues is recommended.
促甲状腺激素分泌型垂体腺瘤较为罕见。它们可能导致一种极其罕见的甲状腺功能亢进形式。由于临床症状被归因于常见类型的甲状腺功能亢进，诊断往往会延迟。诊断包括检测甲状腺功能亢进患者中促甲状腺激素水平升高或正常（未被抑制），以及通过计算机断层扫描或磁共振成像证明垂体腺瘤的存在。促甲状腺激素释放激素试验中的促甲状腺激素反应缺失或不足。当垂体微腺瘤似乎无法检测到时，必须排除常见的选择性垂体对甲状腺激素抵抗综合征。治疗包括切除肿瘤。如果大腺瘤未完全切除，则随后进行垂体外部放疗。如果这种传统治疗没有产生足够的效果，建议使用长效生长抑素类似物进行治疗。
