Pomerantz R J
Division of Infectious Diseases, Jefferson Medical College of Thomas Jefferson University, Philadelphia, USA.
Hosp Pract (1995). 1998 Sep 15;33(9):87-90, 93-5, 99-101. doi: 10.3810/hp.1998.09.108.
Successfully treated patients with no evidence of plasma viremia may continue to harbor stable reservoirs of HIV at multiple sites, including those shielded by blood-tissue barriers. HIV may be controllable, but few believe that it can be eradicated with the limited group of agents now available. Creative new pharmacologic strategies are needed, as well as increased commitment to the development of a safe and effective vaccine.
血浆病毒血症检测呈阴性的成功治疗患者可能在多个部位持续隐匿稳定的HIV病毒库,包括那些受血组织屏障保护的部位。HIV或许可控,但很少有人相信现有的有限药物组合能够将其根除。我们需要创新的新药物策略,同时加大对安全有效疫苗研发的投入。