[Digestive hemorrhage disclosing an angiodysplasia and von Willebrand disease type 2].
作者信息
Lefrançois C, Dubus L, Maurel J, Chiche L, Lavergne J M, Borel-Derlon A
机构信息
Département d'anesthésie-réanimation chirurgicale, hôpital de Bicêtre, France.
出版信息
Ann Fr Anesth Reanim. 1997;16(8):978-81. doi: 10.1016/s0750-7658(97)82149-1.
PMID:9750649
Abstract
The authors report a case of a 76-year-old man, with not past history of abnormal bleeding, who suffered an acute, recurrent, intestinal haemorrhage from extensive angiodysplasia of the colon. Intestinal bleeding and angiodysplasia were associated with a von Willebrand's disease. Genetic analysis showed a point mutation in arginine 611 of the mature von Willebrand's factor subunit (A1 loop) confirming a von Willebrand's disease type 2.
摘要
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