Stein D J, Mendelsohn I, Potocnik F, Van Kradenberg J, Wessels C
Department of Psychiatry, University of Stellenbosch, Tygerberg, South Africa.
Depress Anxiety. 1998;8(1):39-42. doi: 10.1002/(sici)1520-6394(1998)8:1<39::aid-da8>3.0.co;2-0.
Canine acral lick dermatitis (ALD) has been suggested as an animal analogue of obsessive-compulsive disorder (OCD). A series of dogs with ALD or similar conditions were treated with citalopram, the most selective of the selective serotonin reuptake inhibitors. Six of nine (66.7%) dogs showed significant improvement. Given the apparent efficacy of citalopram in the treatment of OCD and related disorders, these data provide further evidence that ALD is a useful animal analogue of OCD.
犬类肢端舔舐性皮炎（ALD）已被认为是强迫症（OCD）的动物类似物。一系列患有ALD或类似病症的犬只接受了西酞普兰治疗，西酞普兰是选择性5-羟色胺再摄取抑制剂中选择性最强的一种。9只犬中有6只（66.7%）表现出显著改善。鉴于西酞普兰在治疗强迫症及相关病症方面的明显疗效，这些数据进一步证明ALD是一种有用的强迫症动物类似物。
