Bar-Lev M, Zajicek G, Michaeli Y, Weinreb M M
Cell Tissue Kinet. 1976 Sep;9(5):413-8. doi: 10.1111/j.1365-2184.1976.tb01291.x.
Crowning of all four rat incisors slows down their eruption rate, leading to a diminution of cell production by the inner enamel epithelium (IEE). The production rate by 100 progenitor cells is dominated as production rate %. The normal IEE in rats weighing 200 g produces daily 67 cells %. In the crowned incisor this rate drops to 15 cells % while during accelerated eruption rate and IEE cell production rate remains unchanged and an eruption of 6-4 mum reflects a production of 1 cell % by the IEE. A method which relates labelled cell displacement along the IEE with its cell production rate is described and its applicability to other cell renewal systems discussed.
大鼠四颗上门齿的牙冠形成会减缓其萌出速度，导致内釉上皮（IEE）的细胞生成减少。以生成率%表示，100个祖细胞的生成速率占主导。体重200克的正常大鼠IEE每日生成67个细胞%。在有牙冠的门齿中，此速率降至15个细胞%，而在加速萌出期间，IEE细胞生成速率保持不变，6 - 4μm的萌出反映IEE生成1个细胞%。本文描述了一种将沿IEE标记细胞的位移与其细胞生成速率相关联的方法，并讨论了其在其他细胞更新系统中的适用性。
