Elias D, Manai M, Eggenspieler P, Julieron M, Girinsky T, Kac J, Ducreux M
Service de Chirurgie Carcinologieque, Institut Gustave-Roussy, Villejuif.
Ann Chir. 1998;52(1):36-40.
The treatment of synchronous esophageal and head and neck carcinomas is difficult.
Retrospective study of 33 patients treated with esophagectomy for an intrathoracic squamous cells carcinoma discovered during pan-endoscopy for a synchronous head and neck cancer.
In 7 cases (21%) it was advanced (pT3-4) esophageal cancers. The hospital mortality was 9%. Five year survival was 18% without stabilization of the survival curve, 60% of patients died of recurrence of tumor.
Esophagectomy is suitable for usT1-2 tumors if surgery is also indicated for the head and neck tumor. Radiochemotherapy is indicated for advanced usT3-4 esophageal tumors or when the treatment of the head and neck tumor is not surgery.
同步性食管癌和头颈部癌的治疗很困难。
对33例因同步性头颈部癌行全内镜检查时发现的胸段鳞状细胞食管癌而接受食管切除术的患者进行回顾性研究。
7例(21%)为进展期(pT3 - 4)食管癌。医院死亡率为9%。五年生存率为18%,生存曲线无稳定趋势,60%的患者死于肿瘤复发。
如果头颈部肿瘤也适合手术,食管切除术适用于usT1 - 2期肿瘤。对于进展期usT3 - 4期食管肿瘤或头颈部肿瘤不适合手术治疗时,应采用放化疗。