Rodier J F, Janser J C, Petit H, Schneegans O, Ott G, Kaissling A, Grob J C, Velten M
Département de Chirurgie Oncologique, Centre Régional de Lutte Contre le Cancer Paul-Strauss, Strasbourg.
Ann Chir. 1998;52(3):229-33.
A study of 50 patients with hyperthyroidism was conducted to evaluate the effect of preoperative administration of Lugol's iodine solution on thyroid blood flow. Highly significant reductions in diameter, time-averaged velocity, and volume flow of the superior thyroid artery were demonstrated after administration of Lugol's solution. The Duplex ultrasound scanning used in this study is a noninvasive, inexpensive, accurate, and reproducible technique suitable for analysis of thyroid blood flow in hyperthyroidism. On the basis of current ultrasonographic results and low postoperative morbidity in patients, Lugol's solution is well tolerated and may be recommended for use before thyroidectomy, especially for diffuse toxic goiters and Graves disease.
对50例甲状腺功能亢进患者进行了一项研究，以评估术前给予卢戈氏碘溶液对甲状腺血流的影响。给予卢戈氏溶液后，甲状腺上动脉的直径、时间平均速度和血流量均显著降低。本研究中使用的双功超声扫描是一种无创、廉价、准确且可重复的技术，适用于分析甲状腺功能亢进患者的甲状腺血流。基于目前的超声检查结果以及患者术后低发病率，卢戈氏溶液耐受性良好，可推荐在甲状腺切除术前使用，尤其是对于弥漫性毒性甲状腺肿和格雷夫斯病。
