Knight D H, Lok J B
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA.
Clin Tech Small Anim Pract. 1998 May;13(2):77-82. doi: 10.1016/S1096-2867(98)80010-8.
The current emphasis on heartworm prevention reflects the dependable protection provided by the monthly administered macrolide endectocides. This article reviews the prerequisites for heartworm transmission and the importance of daily temperature as a limiting factor in determining the seasonality of the transmission period. The practice of some veterinarians to continuously prescribe monthly chemoprophylaxis exaggerates the actual risk of heartworm transmission in most parts of the country and unnecessarily increases the cost of protection to their clients. Guidelines are provided for making an objective, conservative estimate of the earliest and latest dates for administering monthly chemoprophylaxis; and the use of seasonal projections for other clinical applications such as timing and interpretation of heartworm testing are discussed.
当前对预防心丝虫的重视反映了每月施用大环内酯类体内外寄生虫驱杀剂所提供的可靠保护。本文回顾了心丝虫传播的先决条件以及日温度作为决定传播期季节性的限制因素的重要性。一些兽医持续开每月化学预防药的做法夸大了该国大部分地区心丝虫传播的实际风险，并且不必要地增加了客户的保护成本。提供了指导方针，用于客观、保守地估计进行每月化学预防的最早和最晚日期；并讨论了季节性预测在其他临床应用中的使用，如心丝虫检测的时间安排和解读。
