Brodsky M C, Vaphiades M
Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, USA.
Ophthalmology. 1998 Sep;105(9):1686-93. doi: 10.1016/S0161-6420(98)99039-X.
To determine whether magnetic resonance (MR) imaging can be used to predict the presence of elevated intracranial pressure.
Retrospective case series.
Twenty patients with pseudotumor cerebri and 20 control subjects.
Magnetic resonance imaging.
The presence or absence of the following six neuroimaging signs was measured: (1) flattening of the posterior sclera; (2) enhancement of the prelaminar optic nerve; (3) distension of the perioptic subarachnoid space; (4) intraocular protrusion of the prelaminar optic nerve; (5) vertical tortuosity of the orbital optic nerve; and (6) empty sella.
The MR imaging disclosed flattening of the posterior sclera in 80% of patients with pseudotumor cerebri, empty sella in 70%, distension of the perioptic subarachnoid space in 45%, enhancement of the prelaminar optic nerve in 50%, vertical tortuosity of the orbital optic nerve in 40%, and intraocular protrusion of the prelaminar optic nerve in 30%. Each neuroimaging sign was detected in 5% of control subjects, except for enhancement of the prelaminar optic nerve, which was not detected in control subjects. Based on these MR imaging signs, the examiner was able to predict the presence of elevated intracranial pressure in 90% of cases with pseudotumor cerebri and the absence of elevated intracranial pressure in all control subjects.
Elevated intracranial pressure produces a constellation of MR imaging signs that can assist in establishing the diagnosis of pseudotumor cerebri.
确定磁共振成像（MR）是否可用于预测颅内压升高。
回顾性病例系列研究。
20例假性脑瘤患者和20例对照者。
磁共振成像。
测量以下六种神经影像学征象的有无：（1）后巩膜扁平；（2）视盘前视神经强化；（3）视周蛛网膜下腔扩张；（4）视盘前视神经向眼内突出；（5）眶内段视神经垂直迂曲；（6）空蝶鞍。
磁共振成像显示，80%的假性脑瘤患者存在后巩膜扁平，70%有空蝶鞍，45%有视周蛛网膜下腔扩张，50%有视盘前视神经强化，40%有眶内段视神经垂直迂曲，30%有视盘前视神经向眼内突出。除视盘前视神经强化在对照者中未检测到外，每种神经影像学征象在5%的对照者中被检测到。基于这些磁共振成像征象，检查者能够在90%的假性脑瘤病例中预测颅内压升高的存在，并在所有对照者中预测颅内压未升高。
颅内压升高会产生一系列磁共振成像征象，有助于确立假性脑瘤的诊断。
