Steinemann T L, Baltz T C, Lam B L, Soulsby M, Walls R C, Brown H H
Jones Eye Institute, Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock.
Ophthalmology. 1998 Sep;105(9):1739-44. doi: 10.1016/S0161-6420(98)99047-9.
This study aimed to examine ocular rupture force in pig eyes after "minimally invasive radial keratotomy" (MRK) and standard radial keratotomy (SRK).
Experimental study.
A total of 71 pairs of pig eyes (51 control eyes) were examined.
An axial-torsional Materials Testing System (MTS, Eden Prairie, MN) was used to apply blunt force to the corneal surface. A force transducer measured the rupture forces in control eyes and in eyes with MRK or SRK. Five groups of paired eyes were compared: 2.0-mm MRK versus control (N = 12), 3.5-mm MRK versus control (N = 21), 6.5-mm SRK versus control (N = 18), SRK versus 3.5-mm MRK versus 2.0-mm MRK (N = 10).
Ocular rupture force (newtons) was measured.
The mean rupture force in newtons was 746.3 for control eyes, 514.2 for 2.0-mm MRK, 353.1 for 3.5-mm MRK, and 246.2 for SRK. Analysis of variance showed a statistically significant difference (P < or = 0.04) between paired comparisons.
The MRK and SRK significantly weakened ocular integrity compared with control eyes not operated on. MRK required significantly more force to rupture than SRK. MRK eyes, however, ruptured at 50% to 70% of the force required to rupture eyes not operated on. Any patient considering radial keratotomy should be counseled about the risk of greater ocular damage in trauma.
本研究旨在检测“微创放射状角膜切开术”（MRK）和标准放射状角膜切开术（SRK）后猪眼的眼球破裂力。
实验研究。
共检查了71对猪眼（51只对照眼）。
使用轴向扭转材料测试系统（MTS，明尼苏达州伊甸草原市）对角膜表面施加钝力。力传感器测量对照眼以及接受MRK或SRK手术眼的破裂力。比较了五组配对眼：2.0毫米MRK与对照（N = 12），3.5毫米MRK与对照（N = 21），6.5毫米SRK与对照（N = 18），SRK与3.5毫米MRK与2.0毫米MRK（N = 10）。
测量眼球破裂力（牛顿）。
对照眼的平均破裂力为746.3牛顿，2.0毫米MRK为514.2牛顿，3.5毫米MRK为353.1牛顿，SRK为246.2牛顿。方差分析显示配对比较之间存在统计学显著差异（P≤0.04）。
与未手术的对照眼相比，MRK和SRK显著削弱了眼球完整性。MRK破裂所需的力明显大于SRK。然而，MRK眼破裂时所需的力是未手术眼的50%至70%。任何考虑进行放射状角膜切开术的患者都应被告知创伤时眼球受损风险更高。
