Araújo J F, Souza M R, Sperlescu A, Balbo R J
Departamento de Patologia, Faculdade de Ciências Médicas, Pontifícia Universidade Católica de Campinas, Brasil.
Arq Neuropsiquiatr. 1998 Sep;56(3A):486-90. doi: 10.1590/s0004-282x1998000300022.
We present the case of a 8-years-old boy, admitted with a history of headache, nausea and vomiting. Cerebral angiography showed a non-vascular mass on frontal lobe. The patient underwent craniotomy and the lesion was removed. Neuropathological study revealed that the tumor was a ganglioglioma. The patient received pos-operative radiotherapy. On follow-up, 16 years after, a computed tomographic scan showed a recurrence of the tumor, and a second surgery revealed a glioblastoma multiform. Gangliogliomas are rare tumors of the central nervous system containing neoplastic ganglion cells and low grade neoplastic glial cells. The malignant degeneration occurs only in the glial component, so the prognosis of these tumors is related to the grade of that component.
我们报告一例8岁男孩的病例，该男孩因头痛、恶心和呕吐病史入院。脑血管造影显示额叶有一个非血管性肿块。患者接受了开颅手术并切除了病变。神经病理学研究显示该肿瘤为神经节胶质瘤。患者接受了术后放疗。随访16年后，计算机断层扫描显示肿瘤复发，二次手术显示为多形性胶质母细胞瘤。神经节胶质瘤是中枢神经系统罕见的肿瘤，包含肿瘤性神经节细胞和低级别肿瘤性胶质细胞。恶性变仅发生在胶质成分中，因此这些肿瘤的预后与该成分的分级有关。
