Solomon R
Harvard Medical School, and the Renal Division, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Semin Nephrol. 1998 Sep;18(5):551-7.
Radiocontrast-induced nephropathy (RCIN) is a common cause of acute renal failure. It results from an ischemic injury to the medullary portion of the kidney secondary to intense renal vasoconstriction. Patients with pre-existing renal insufficiency, diabetes, congestive heart failure, taking certain medications, and exposed to large volumes of high osmolar contrast are at increased risk of developing RCIN. Prophylaxis of high-risk patients by careful hydration and avoidance of exacerbating factors can minimize the incidence of RCIN.
造影剂肾病（RCIN）是急性肾衰竭的常见病因。它是由于强烈的肾血管收缩继发肾髓质缺血性损伤所致。已有肾功能不全、糖尿病、充血性心力衰竭、服用某些药物以及暴露于大量高渗造影剂的患者发生RCIN的风险增加。通过仔细补液和避免加重因素对高危患者进行预防可将RCIN的发生率降至最低。
